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中文名稱：CASP14抗原（重組蛋白）

英文名稱：CASP14 Antigen (Recombinant Protein)

儲存：冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 6-242 amino acids of human CASP14

技術規(guī)格

Full name:

caspase 14, apoptosis-related cysteine peptidase

Swissprot:

P31944

Gene Accession:

BC069541

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

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CASP14抗原（重組蛋白）說明書
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021-54845833/15800441009

ELISA試劑盒

PCR試劑盒

生化試劑盒

細胞系

細胞庫

基礎培養(yǎng)基

完全培養(yǎng)基

原代細胞

細胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

標準品

血清

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CASP14抗原（重組蛋白）

Full name:	caspase 14, apoptosis-related cysteine peptidase
Swissprot:	P31944
Gene Accession:	BC069541
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.