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中文名稱：BAD抗原（重組蛋白）

英文名稱：BAD Antigen (Recombinant Protein)

儲(chǔ) 存：冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 15-168 amino acids of human BAD

技術(shù)規(guī)格

Full name:

BCL2-associated agonist of cell death

Synonyms:

BBC2; BCL2L8

Swissprot:

Q92934

Gene Accession:

BC001901

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

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BAD抗原（重組蛋白）

Full name:	BCL2-associated agonist of cell death
Synonyms:	BBC2; BCL2L8
Swissprot:	Q92934
Gene Accession:	BC001901
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.