購(gòu)物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
Background:
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Applications:
WB
Name of antibody:
IL4
Immunogen:
Synthesized peptide derived from C-terminal of human IL4.
Full name:
interleukin 4
Synonyms：
BSF1; IL-4; BCGF1; BSF-1; BCGF-1
SwissProt:
P05112
WB Predicted band size:
17 kDa
WB Positive control:
Hela cells lysate
WB Recommended dilution:
500-3000
