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中文名稱 : 小鼠抗FOLH1單克隆抗體

英文名稱 : Anti-FOLH1 mouse monoclonal antibody

別名 : FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA

儲(chǔ) 存 : 冷凍（-20℃）避光

抗原 : FOLH1

宿主 : Mouse

反應(yīng) 種屬 : Human, Mouse

相關(guān) 類別 : 一抗

標(biāo) 記物 : Unconjugate

克隆類型 : mouse monoclonal

技術(shù)規(guī)格

Background:

This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq].

Applications:

WB, IHC, IF, FC

Name of antibody:

FOLH1

Immunogen:

Fusion protein of human FOLH1

Full name:

folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1

Synonyms:

FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA

SwissProt:

Q04609

IHC positive control:

adenocarcinoma of human endometrium tissue and carcinoma of human prostate tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

84 kDa

WB Positive control:

Hela, SVT2, COS7, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000

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小鼠抗FOLH1單克隆抗體

Background:	This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq].
Applications:	WB, IHC, IF, FC
Name of antibody:	FOLH1
Immunogen:	Fusion protein of human FOLH1
Full name:	folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1
Synonyms:	FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA
SwissProt:	Q04609
IHC positive control:	adenocarcinoma of human endometrium tissue and carcinoma of human prostate tissue
IHC Recommend dilution:	30-150
WB Predicted band size:	84 kDa
WB Positive control:	Hela, SVT2, COS7, MDCK, PC12, MCF-7 cell lysates
WB Recommended dilution:	500-2000