購物車
幫助
021-54845833/15800441009
中文名稱：兔抗CDH12多克隆抗體
英文名稱： Anti-CDH12 rabbit polyclonal antibody
儲 存： 冷凍（-20℃）
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CDH12 |
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Immunogen: |
Synthetic peptide of human CDH12 |
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Full name: |
cadherin 12 |
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Synonyms: |
CDHB |
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SwissProt: |
P55289 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer and Human liver cancer |
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IHC Recommend dilution: |
25-50 |
