購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1gene. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. |
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Applications: |
ELISA, WB |
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Name of antibody: |
BMI1 |
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Immunogen: |
Fusion protein of human BMI1 |
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Full name: |
BMI1 polycomb ring finger oncogene |
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Synonyms： |
PCGF4; RNF51; FLVI2/BMI1 |
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SwissProt: |
P35226 |
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ELISA Recommended dilution: |
1000-2000 |
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WB Predicted band size: |
37 kDa |
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WB Positive control: |
231 and A549 cells, hela cells and mouse brain tissue |
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WB Recommended dilution: |
200-1000 |
