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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW22563
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:75
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中文名稱:兔抗STX5多克隆抗體

英文名稱: Anti-STX5 rabbit polyclonal antibody

別      名: syntaxin 5; SED5; STX5A

相關(guān)類別: 一抗

儲(chǔ)      存: 冷凍(-20℃)

宿      主: Rabbit

抗      原: STX5

反應(yīng)種屬: Human, Mouse, Rat

標(biāo)  記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

The membrane protein syntaxin 5 (STX5) is a key component of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complexes that regulate cellular protein transport, vesicle docking, and membrane fusion. Syntaxin 5 protein is found as a 42 kDa ("long") protein localized to the Golgi complex and endoplasmic reticulum, and a “short” 35 kDa isoform localized primarily to the Golgi. Formation of the syntaxin 5 SNARE complex, which also includes proteins Sec22B, Bet1, GOSR1, GOSR2, and Ykt6, allows for regulation of ER-to-Golgi transport, intra-Golgi transport, and endosome-to-Golgi retrograde transport. Research studies indicate that the syntaxin 5 SNARE complex also plays an essential role in autophagy following autophagosome formation. Intracellular protein transport mediated by the syntaxin 5 complex is required for transport and localized activity of lysosomal proteases. The experimental reduction or deletion of syntaxin 5 complex components results in non-functional lysosomes and accumulation of autophagosomes.

Applications:

ELISA, WB, IHC

Name of antibody:

STX5

Immunogen:

Fusion protein of human STX5

Full name:

syntaxin 5

Synonyms:

SED5; STX5A

SwissProt:

Q13190

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

40 kDa

WB Positive control:

HepG2, A431 and Raji cell lysates

WB Recommended dilution:

500-2000





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