購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PRMT5多克隆抗體
英文名稱： Anti-PRMT5 rabbit polyclonal antibody
別 名： JBP1, SKB1, IBP72, SKB1Hs, HRMT1L5
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PRMT5
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Protein arginine methyltransferase 5 has been shown to interact with WD repeat-containing protein 77, CLNS1A, Janus kinase 2, SNRPD3 and SUPT5H.Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
PRMT5 |
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Immunogen: |
Synthetic peptide of human PRMT5 |
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Full name: |
protein arginine methyltransferase 5 |
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Synonyms： |
JBP1, SKB1, IBP72, SKB1Hs, HRMT1L5 |
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SwissProt: |
O14744 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human breast cancer and Human tonsil |
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IHC Recommend dilution: |
15-50 |
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WB Predicted band size: |
71 kDa |
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WB Positive control: |
K562, hela and 293T cells |
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WB Recommended dilution: |
200-1000 |
