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中文名稱：兔抗GNE多克隆抗體

英文名稱： Anti-GNE rabbit polyclonal antibody

別名： NM; DMRV; IBM2; Uae1; GLCNE

相關(guān)類別：一抗

儲存： 冷凍（-20℃）避光

宿主： Rabbit

抗原： GNE

反應(yīng)種屬： Human Mouse

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [

Applications:

WB, IHC

Name of antibody:

GNE

Immunogen:

Synthesized peptide derived from C-terminal of human GNE.

Full name:

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

Synonyms：

NM; DMRV; IBM2; Uae1; GLCNE

SwissProt:

Q9Y223

IHC positive control:

Human placenta tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

79 kDa

WB Positive control:

NIH/3T3 cells lysate

WB Recommended dilution:

500-3000

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細胞專用培養(yǎng)基

菌株

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病理染色液

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兔抗GNE多克隆抗體

Background:	The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [
Applications:	WB, IHC
Name of antibody:	GNE
Immunogen:	Synthesized peptide derived from C-terminal of human GNE.
Full name:	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Synonyms：	NM; DMRV; IBM2; Uae1; GLCNE
SwissProt:	Q9Y223
IHC positive control:	Human placenta tissue
IHC Recommend dilution:	50-100
WB Predicted band size:	79 kDa
WB Positive control:	NIH/3T3 cells lysate
WB Recommended dilution:	500-3000