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021-54845833/15800441009
中文名稱(chēng)： 兔抗PDCD6IP多克隆抗體
英文名稱(chēng)： Anti-PDCD6IP rabbit polyclonal antibody
別 名： AIP1; ALIX; HP95; DRIP4
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PDCD6IP
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. |
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Applications: |
ELISA, WB |
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Name of antibody: |
PDCD6IP |
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Immunogen: |
Synthetic peptide of human PDCD6IP |
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Full name: |
programmed cell death 6 interacting protein |
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Synonyms: |
AIP1; ALIX; HP95; DRIP4 |
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SwissProt: |
Q8WUM4 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
96 kDa |
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WB Positive control: |
Hela cell lysate |
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WB Recommended dilution: |
200-1000 |
