購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
EXD2 |
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Immunogen: |
Fusion protein of human EXD2 |
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Full name: |
exonuclease 3'-5' domain containing 2 |
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Synonyms: |
EXDL2; C14orf114 |
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SwissProt: |
Q9NVH0 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human ovarian cancer |
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IHC Recommend dilution: |
40-200 |
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WB Predicted band size: |
70 kDa |
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WB Positive control: |
Mouse testis tissue lysate |
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WB Recommended dilution: |
200-1000 |
