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中文名稱: 兔抗DUSP11多克隆抗體

英文名稱: Anti-DUSP11 rabbit polyclonal antibody

別名: PIR1

儲(chǔ) 存: 冷凍（-20℃）

抗原: DUSP11

宿主: Rabbit

相關(guān)類別: 一抗

反應(yīng)種屬: Human

標(biāo) 記物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.

Applications:

ELISA, IHC

Name of antibody:

DUSP11

Immunogen:

Full length fusion protein

Full name:

dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)

Synonyms：

PIR1

SwissProt:

O75319

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

30-150

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菌株

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兔抗DUSP11多克隆抗體

Background:	The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.
Applications:	ELISA, IHC
Name of antibody:	DUSP11
Immunogen:	Full length fusion protein
Full name:	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
Synonyms：	PIR1
SwissProt:	O75319
ELISA Recommended dilution:	2000-10000
IHC positive control:	Human liver cancer
IHC Recommend dilution:	30-150