購(gòu)物車(chē)
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021-54845833/15800441009
中文名稱(chēng)： 兔抗MBP多克隆抗體
英文名稱(chēng)： Anti-MBP rabbit polyclonal antibody
別 名： MGC99675
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： MBP
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation. |
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Applications: |
WB |
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Name of antibody: |
MBP |
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Immunogen: |
Synthetic peptide of human MBP |
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Full name: |
myelin basic protein |
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Synonyms： |
MGC99675 |
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SwissProt: |
P02686 |
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WB Predicted band size: |
33 kDa |
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WB Positive control: |
Rat brain, Mouse brain and Rat hippocampus Tissue |
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WB Recommended dilution: |
500-1000 |
