購物車
幫助
021-54845833/15800441009
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Full name: |
presenilin associated, rhomboid-like |
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Synonyms: |
PSARL; PSARL1; RHBDS1; PRO2207; PSENIP2 |
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Swissprot: |
Q9H300 |
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Gene Accession: |
BC014058 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. |
