購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：SPHK2抗原（重組蛋白）
英文名稱： SPHK2 Antigen (Recombinant Protein)
別 名： SK 2; SK-2; SPK 2; SPK-2
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human SPHK2 |
|
Full name: |
sphingosine kinase 2 |
|
Synonyms: |
SK 2; SK-2; SPK 2; SPK-2 |
|
Swissprot: |
Q9NRA0 |
|
Gene Accession: |
BC006161 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
