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  • PSMD3抗原(重組蛋白)

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    價(jià)格:
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17098
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:40
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中文名稱: PSMD3抗原(重組蛋白)

英文名稱: PSMD3 Antigen (Recombinant Protein)

別       名: S3; P58; RPN3; TSTA2

儲(chǔ)       存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概述

Fusion protein corresponding to C terminal 250 amino acids of human PSMD3

技術(shù)規(guī)格

Full name:

proteasome (prosome, macropain) 26S subunit, non-ATPase, 3

Synonyms:

S3; P58; RPN3; TSTA2

Swissprot:

O43242

Gene Accession:

BC012302

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count.

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