購物車
幫助
021-54845833/15800441009
中文名稱： CD27抗原（重組蛋白）
英文名稱： CD27 Antigen (Recombinant Protein)
別 名： T14; S152; Tp55; TNFRSF7; S152. LPFS2
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 20-191 amino acids of human CD27 |
|
Full name: |
CD27 molecule |
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Synonyms: |
T14; S152; Tp55; TNFRSF7; S152. LPFS2 |
|
Swissprot: |
P26842 |
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Gene Accession: |
BC012160 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. |
