購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： ATIC抗原（重組蛋白）
|
Full name: |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
|
Synonyms: |
PURH; AICAR; AICARFT; IMPCHASE; HEL-S-70p |
|
Swissprot: |
P31939 |
|
Gene Accession: |
BC008879 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. |
