購(gòu)物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
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Background: |
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ITGB2 |
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Immunogen: |
Fusion protein of human ITGB2 |
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Full name: |
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
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Synonyms： |
LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1 |
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SwissProt: |
P05107 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
25-100 |
